I am not certain if principled exclusion is applicable when it concerns humanity's pursuit of a state of fulfillment of ultimate wisdom.
Albert Einstein was a presumed 'dreamer'. His teachers described him as not social, mentally slow and always away in his own stupid dreams. He didn't speak a word until he was 4 years old and couldn't read until he was 7 years old. In children with Dyslexia it is named "Einstein syndrome".
Professor
Monica Gagliano (
Do Plants Have Something To Say?, New York Times) connects with plants by use of psychoactive plants. According to some (e.g.
consul in this topic), she can be considered a drug addict that produces a bunch of unscientific baloney (i.e. her vision should be excluded because of the 'drug user' aspect that you mentioned)
What is wise? If wisdom cannot be defined, then, perhaps principled exclusion (i.e. based on definitions) should not be an option when the intention is to serve the potential to achieve a state of wisdom.
With regard to the criteria for an artist or entertainer to have an
aim at truth. Would that be wise? To serve the purpose of wisdom, one should be able to make a case. It may seem evident that an aim at truth should be a core quality of wisdom, however, to actually serve wisdom, one should be able to provide an argumentative foundation.
What is truth? How can one aim at it without knowing?
The following article shows how low developed mankind is in 2020 with regard to morality.
(2020)
How we make moral decisions
The researchers now hope to explore the reasons why people sometimes don't seem to use universalization in cases where it could be applicable, such as combating climate change. One possible explanation is that people don't have enough information about the potential harm that can result from certain actions, Levine says.
https://phys.org/news/2020-10-moral-decisions.html
The scientists write that they "hope" that humanity / science will investigate the reasons why people sometimes do not use the "universalization principle" for moral considerations and decisions.
In 2020, the
universalization principle appears to be the only method that is considered available for guiding human action and science.
How could the universalisation principle protect Nature when faced with a potential trillion USD synthetic biology revolution that reduces plants and animals to meaningless beyond the value that a company can "see" in them?
What other method would be possible for moral consideration in the interest of Nature?
Humans seem to be so low developed with regard to morality in 2020 that they don't even know where to start searching. Scientists can only "hope" that humans will start searching soon.
In my opinion, philosophy and morality may play a vital role in the next 100 years to allow humans to evolve into a 'moral being' to secure longer term prosperity and survival.